Gastrointestinal Disorders

Inflammation: Mast cells, eosinophils, and Th2 immune cells release histamine, leukotrienes, and cytokines that swell the airway tissue.
Bronchoconstriction: The smooth muscles surrounding the airways contract sharply, narrowing airflow passages.
Mucus overproduction: Chronic inflammation triggers excess mucus that further blocks breathing.

Subtypes

Crohn's Disease
Irritable Bowel Syndrome (IBS)

Description

Gastrointestinal disorders affect the digestive system, including the stomach, intestines, and colon. These conditions often involve inflammation, dysbiosis, immune dysfunction, and impaired gut barrier function.