Mental Disorder

Description

Mental disorders share common biological foundations involving metabolic dysfunction, inflammation, neurotransmitter imbalance, HPA-axis dysregulation, and nutrient deficiencies. High-carbohydrate intake and repeated insulin spikes contribute to unstable blood sugar, insulin resistance, and increased production of inflammatory cytokines (IL-6, TNF-α). These factors damage the gut barrier (leaky gut), allowing endotoxins to enter the bloodstream and trigger systemic and neuroinflammation. Neuroinflammation disrupts communication in key brain regions such as the prefrontal cortex, amygdala, hippocampus, and basal ganglia, impairing cognition, emotional regulation, motivation, and impulse control.

Chronic stress and blood sugar instability dysregulate the HPA axis, elevating cortisol and adrenaline. Persistent cortisol alters dopamine, serotonin, glutamate, and GABA signaling, producing anxiety, depression, mood swings, irritability, sleep disruption, and cognitive impairment. Mitochondrial dysfunction further reduces neuronal energy production, destabilizing brain networks involved in mood and thought regulation.

Nutrient deficiencies—particularly zinc, magnesium, iron, B-vitamins, omega-3s, and essential amino acids—are common contributors. These nutrients are required for neurotransmitter synthesis, receptor function, myelination, and mitochondrial energy production. Low intake of animal-based foods is a major cause of these deficiencies.

Fasting, ketogenic diets, and carnivore diets provide metabolic stability by reducing inflammation, improving insulin sensitivity, and supplying ketones that bypass impaired glucose metabolism in the brain. Ketones reduce neuroinflammation, increase GABA, stabilize glutamate, support dopamine regulation, and enhance mitochondrial function. Stable blood sugar removes cortisol spikes and improves emotional control and cognitive clarity. High intake of nutrient-dense animal foods restores zinc, iron, magnesium, omega-3s, and amino acids required for optimal brain function. Together, these interventions address the common biological roots of most mental disorders—reducing symptoms and restoring cognitive and emotional stability.

Sources

[1] Leaky gut and autoimmune diseases
[ 1 ] Fasano A et al. (2012) DOI PMID
[2] Insulin resistance as a predictor of age-related diseases
[ 2 ] F S Facchini et al. (2001) DOI PMID